PVP (polyvinylpyrrolidone) yog ib qho khoom siv dav siv hauv tshuaj, khoom noj, tshuaj pleev ib ce, thiab lwm yam lag luam. PVP yog dej-soluble, non-toxic, thiab biocompatible polymer uas yog muab los ntawm cov tshuaj tiv thaiv ntawm N-vinylpyrrolidone monomer thiab hydrogen peroxide.
PVP yog cov khoom siv ntau yam uas tuaj yeem siv rau ntau lub hom phiaj. Nws zoo heev solubility thiab adhesion zog ua rau nws zoo tagnrho binder thiab disintegrant rau ntsiav tshuaj ntau lawm. Nws kuj yog siv los ua tus neeg sawv cev txheej los txhim kho cov tsos, kev ruaj ntseg, thiab kev ua tau zoo ntawm cov ntsiav tshuaj. Tsis tas li ntawd, PVP tuaj yeem siv los ua tus neeg nqa khoom rau kev xa tshuaj, xws li nanoparticles, microparticles, thiab liposomes, txhawm rau txhim kho bioavailability thiab tswj kev tso tawm ntawm cov tshuaj.
Tsis tas li ntawd, PVP yog siv hauv kev lag luam zaub mov ua emulsifier, stabilizer, thiab thickener. Nws tuaj yeem txhim kho kev ntxhib los mos, sib xws, thiab txee lub neej ntawm cov khoom noj. PVP feem ntau yog siv rau hauv dej haus, khoom noj khoom haus, khoom noj khoom haus, thiab cov khoom noj nqaij.
Hauv kev lag luam tshuaj pleev ib ce, PVP yog siv los ua tus neeg sawv cev khi, zaj duab xis-yav dhau los, thiab viscosity enhancer. Nws tuaj yeem txhim kho qhov kev ntxhib los mos, nthuav dav, thiab ua kom zoo nkauj ntawm cov khoom siv tshuaj pleev ib ce, xws li cream, tshuaj pleev, tshuaj zawv plaub hau, thiab tshuaj pleev plaub hau. PVP tseem tuaj yeem ua raws li kev tiv thaiv ntawm daim tawv nqaij thiab plaub hau, tiv thaiv kom tsis txhob ya raws thiab kev puas tsuaj los ntawm ib puag ncig.
Txawm hais tias nws muaj ntau yam kev siv, PVP suav tias yog kev nyab xeeb rau tib neeg noj thiab siv. Kev tshawb fawb dav tau pom tias PVP muaj toxicity tsawg, tsis tshua muaj allergenicity, thiab tsis muaj carcinogenicity los yog mutagenicity. PVP feem ntau lees paub tias muaj kev nyab xeeb (GRAS) los ntawm US Food and Drug Administration (FDA) thiab tau pom zoo los ntawm cov tswj hwm thoob ntiaj teb.
Hauv kev xaus, PVP yog qhov muaj txiaj ntsig thiab muaj txiaj ntsig zoo uas tau siv dav hauv kev lag luam tshuaj, zaub mov, tshuaj pleev ib ce, thiab lwm yam lag luam. Nws cov khoom tshwj xeeb ua rau nws muaj qhov zoo tshaj plaws rau ntau daim ntawv thov, thiab nws qhov profile muaj kev nyab xeeb kom ntseeg tau tias nws tuaj yeem siv nrog kev ntseeg siab. Raws li kev siv thev naus laus zis txuas ntxiv mus, PVP zoo li yuav pom kev siv tshiab thiab siv tshiab yav tom ntej.