Hauv kev tiv thaiv kev tiv thaiv tus kab mob, kev qhia tawm ntawm cov tshuaj tua kab mob dav dav vim nws cov iodine thiab polyvinylprolidone. Qhov kev npaj no tuaj yeem ua tsis tau zoo cov kab mob, cov kab mob fungi thiab kab mob, thiab muaj cov tawv nqaij tsawg thiab muaj kev nyab xeeb. Cov kev tshawb fawb soj ntsuam tau pom tias cov kab mob kev phais mob plab qis dua los ntawm pab pawg sib xyaw ua ke, uas yog qis dua li cov pab pawg tshuaj tua kab mob. Kev kho cov neeg mob ceev ceev ntawm cov neeg mob tau nrawm dua (lees paub tias cov neeg hauv tsev kho mob tau luv dua), thiab cov neeg hauv tsev kho mob tau luv dua), thiab cov neeg hauv tsev kho mob kom luv dua
Cov txheej txheem
2. Tam sim no cov xwm txheej thiab kev phom sij ntawm phais kab mob
3. Mechanism ntawm Kev Ua ntawm Povidone-iodine
4. Daim ntawv thov ntawm risidone-iodine hauv kev tiv thaiv ntawm phais kab mob
5. Qhov tseem ceeb ntawm kev risidone-iodine
6. Kev ua lag luam cov kev cia siab thiab kev txhim kho cov qauv ntawm kev sib tw ntawm kev-iodine
Raws li qhov tseem ceeb ntawm kev kho ntau cov kab mob hauv cov txiaj ntsig niaj hnub, kev kho mob hauv kev txuag lub neej tsis suav thiab txhim kho cov neeg mob txoj kev noj qab haus huv. Txawm li cas los xij, kev phais kab mob (SSI), kev txhawb nqa postativeation, ib txwm yog ib qho kev sib tw uas hnyav heev. Kev phais neeg tus kab mob tsis yog ncua sij hawm tus neeg mob lub siab kho mob thiab mob hlwb, tab sis tej zaum yuav raug txim tus neeg mob lub neej hnyav. Raws li kev txheeb cais los ntawm lub Koom Haum Ntiaj Teb Kev Noj Qab Haus Huv (Leej twg) phais kab mob tshwm sim hauv kwv yees li ntawm txhua qhov chaw uas muaj qee cov khoom siv tsawg. Yog li ntawd, nrhiav kev ntsuas kev tiv thaiv kom tsis txhob muaj kev phais kab mob tau dhau los ua qhov teeb meem tseem ceeb uas yuav tsum tau hais kom sai tau nyob hauv zej zog khomob. Nyob rau hauv xyoo tas los,risidone-iodine,Raws li kev siv tshuaj tua kab mob zoo, muaj kev nyab xeeb thiab dav tau ua rau muaj kev tiv thaiv zoo thiab tau maj mam los ua tus neeg ua haujlwm muaj zog rau cov neeg ua haujlwm kho mob.
2. Tam sim no cov xwm txheej thiab kev phom sij ntawm phais kab mob
● Kev phais mob kis tus kab mob kis
Muaj ntau qhov sib txawv hauv qhov tshwm sim ntawm kev phais mob rau ntau yam kev phais. Cov hauv qab no yog cov txheeb cais ntawm qhov tshwm sim ntawm kev phais kab mob rau hom kev phais:
| Hom Kev Kho Mob | Kev Pab Cuam Tshuam (%) |
| Kev phais kom huv | 1月5日 |
| Kev phais mob huv huv | 5月10日 |
| Kev phais mob | 10月20日 |
| Tsis muaj mob phais | >20 |
Los ntawm cov ntaub ntawv, nws tuaj yeem pom tias kev nyiam huv ntawm qhov phais phais mob txo, qhov kis tau tus kab mob uas pom tau tus kab mob meej.
● Kev lag luam kev lag luam ntawm kev phais mob
Kev phais mob tus mob tuaj yeem ua rau muaj kev siv nqi kho mob tseem ceeb. Raws li kev kawm los ntawm cov chaw rau tus kab mob kev tswj hwm thiab kev tiv thaiv (CDC), {{1, {} {3}}. Hauv kuv lub teb chaws, kev kawm txog Tsev Kho Mob Qib Tertiary loj tau txais kev phais mob txog RMB 15, {} {}} sib piv nrog cov neeg mob tsis muaj kev kis mob. Cov nqi ntxiv no suav nrog cov nqi txaj, thiab cov nqi tshuaj muaj los ntawm kev ua haujlwm hauv tsev kho mob, thiab cov nqi tshwj xeeb rau kev kho mob.
Kev cuam tshuam ntawm kev phais mob kis tus neeg mob
Kev phais mob tsis yog ua rau cov neeg mob ua rau mob lub qhov ntswg, tsis muaj kev nyuaj, thiab cuam tshuam rau tus neeg mob lub ntsej muag thiab limb ua haujlwm. Cov kab mob hnyav tuaj yeem ua rau muaj kev kis tus kab mob hnyav, xws li sepsis, nce txoj kev pheej hmoo tuag. Cov kev tshawb fawb pom tau qhia tias kev tuag ntawm cov neeg mob nrog tus kab mob uas raug phais mob los ntawm kev phais mob tuaj yeem ua siab ntev li 10% mus rau 30%.
3. Mechanism ntawm Kev Ua ntawm Povidone-iodine
● Sib xyaw thiab cov yam ntxwv ntawm povidone iodine
Pov mus txog iodine (PVP-i) yog ib txoj kev ua los ntawm cov complexation ntawm iodine thiab polyvinylprolidone (PVP). PVP yog cov tshuaj polymular siab siab nrog dej solubility thiab biocompatibility. Nws tuaj yeem tsim cov ruaj khov nrog iodine, yog li ntawd iodine maj mam tso tawm hauv kev daws teeb meem, yog li ntev lub bactericidal cuam tshuam ntawm iodine. Povivone iodine daws yog feem ntau yog cov kua av liab nrog cov khoom ruaj khov, tsis muaj kev cuam tshuam cov ntxhiab tsw, thiab kev zoo rau cov tawv nqaij thiab cov ntaub nyias nyias nyias.
● S yam tsis muaj menyuam txoj ntsiab cai
Cov kab mob ntawm cov nyhuv ntawm cov kab mob ntawm iodine feem ntau yog raws li cov khoom siv oxidizing muaj zog ntawm iodine. Thaum Povligone iodine los rau hauv kev sib cuag nrog pathogens xws li cov kab mob thiab cov kab mob me me hauv cov kab mob ntawm cov kab mob ntawm cov kab mob, ua tiav lub hom phiaj ntawm kom tsis muaj menyuam thiab kev tsis muaj kab mob. Povtxwv ntawm Iodine muaj ntau yam kev tua cov teebmeem ntawm ntau yam kab mob staphyncus, nyob rau hauv ib qho kev sim siab tawv Staphylococcus Aure, thiab Almerida Coli, thiab Candida Albicans ntawm a tua tus nqi ntawm ntau dua 99.9%.
4. Daim ntawv thov ntawm risidone-iodine hauv kev tiv thaiv ntawm phais kab mob
● Cov tawv nqaij npaj ua ntej
Kev npaj tawv tawv nqaij yog qhov tseem ceeb ntawm kev tiv thaiv kev phais mob. Cov txheej txheem npaj ua ntej ntawm cov kab mob feem ntau siv cov tshuaj tua kab mob xws li dej cawv thiab cov tshuaj tua kab mob muaj qee yam kev haus dej cawv thiab cov kev xav tau ntawm iodine.Pov Thev iodione tov 25655-41-8 50 kg lossis 200kg \/ nruas,Raws li hom tshiab ntawm cov tshuaj tua kab mob ua ntej cov tshuaj tua kab mob, muaj qhov zoo pom tseeb. Ib multicenter randomized tswj kev sim nrog 5 {0 0 Cov neeg mob tau faib lawv ua ob pawg. Ib pab pawg siv pov thawj-iodine rau kev ntxuav cov tawv nqaij ua ntej, thiab lwm pab pawg siv cov tshuaj lom neeg cov tshuaj lom neeg cov tshuaj lom neeg cov tshuaj lom neeg. Cov txiaj ntsig tau pom tias qhov tshwm sim ntawm kev phais mob kis tau tus kab mob hauv lub ntsej muag-iodine pab pawg yog 2.4% hauv Iodine-Cawv Pawg (P <0.05).
● StralaOperatitatare phais dej
Thaum lub sijhawm ua haujlwm, muab cov ntshav phais tau zoo siv tau cov ntshav, cov ntaub mos mos thiab cov kab mob hauv kev mob nkeeg.Pov thawj iodine dawsKev daws teeb meem yog qhov kev xaiv zoo tshaj plaws rau kev phais mob hauv kev phais dej vim nws cov khoom siv zoo thiab cov dej tsis zoo. Kev tshawb fawb pom tau tias intraoperatitation txwv nrog {{{}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}. Piv txwv li, hauv kev kawm ntawm kev phais mob plab, cov pab pawg sim siv cov khoom siv pov thawj rau cov kev phais mob ua kom muaj kev phais cov kua qab. Postoperative taug qab pom tias qhov tshwm sim ntawm kev phais mob phais tau yog 3.2%, thiab qhov sib txawv yog qhov tseem ceeb tshaj plaws (P <0.05).
● Kev saib xyuas lub txhab
Kev saib xyuas qhov txhab txhab mob postoperative kuj tseem tseem ceeb rau kev tiv thaiv kev phais mob. Povivone-iodine tuaj yeem siv rau kev ua kom lub qhov txhab hloov pauv thiab hnav khaub ncaws huv si thiab txhawb kev kho kom zoo. Hauv kev tshawb fawb ntawm 100 Orthopedic phais cov neeg mob, txhua tus neeg mob cov qhov txhab postoperative raug saib xyuas nrog kev sib tw-iodine. Cov txiaj ntsig tau pom tias tsuas yog muaj mob kis tau tus kab mob ntawm 1%, qhia tau tias muaj tus kab mob-Iodine tuaj yeem ua lub luag haujlwm zoo rau kev tiv thaiv kab mob hauv kev mob ncua lub qhov txhab.
5. Qhov tseem ceeb ntawm kev risidone-iodine
Dav-spectrum kom tsis muaj menyuam yam tsis muaj cov txiv ntoo tuag
Pov pov thawj - iodine ua raws li "txhua - kev tiv thaiv kev tiv thaiv", muaj txiaj ntsig zoo tua cov kab mob ntau haiv neeg. Pathogens li Staphylococcus aureus thiab eschchia coli tsis tuaj yeem khiav nws qhov kev txiav txim. Nws precisely lub hom phiaj ob leeg gram - zoo thiab gram - tsis zoo, erecting ib qho "breccacterial" rau kev phais mob.
Kev nyab xeeb siab ua rau tib neeg xav tias yog yooj yim
Pov pov thawj - iodine yog heev "maj mam" rau daim tawv nqaij thiab cov khaub hlab me me nrog kev voos tsawg. Qee tus neeg mob tsis muaj qhov tsis xis nyob lossis ua xua rau thaum siv tau. Yog li, nws haum rau txhua tus neeg mob, tshwj xeeb yog cov tawv nqaij rhiab lossis tsis muaj zog los sis dav hlau nws cov ntawv thov.
Synergistic nyhuv txhim kho zog
Thaum Povidone - iodine ua ke nrog cov tshuaj tua kab mob xws li levofledloxacin, lawv ua raws li cov neeg koom tes TACKS, muaj zog ua cov nyhuv muaj zog. Ua haujlwm ua ke, lawv nthuav dav cov tshuaj tua kab mob thiab txhim kho cov tshuaj tua kab mob, nrog rau "1 + 1 ..." tau txais kev pab tiv thaiv kev phais mob.
Txhawb kho kom kho thiab nrawm rov qab
Povtxwv iodine tsis yog txwv tsis pub muaj kev kis tau tab sis kuj nquag txhawb kev kho mob. Nws ua kom nrawm nrawm thiab kho los ntawm kev txhim kho lub qhov txhab ib puag ncig hauv zos, ua kom kho kom zoo dua. Cov neeg luv luv no tus neeg mob lub tsev kho mob nyob, muaj kev mob siab rau lawv, thiab txhim kho kom rov zoo tag nrho.
6. Kev ua lag luam cov kev cia siab thiab kev txhim kho cov qauv ntawm kev sib tw ntawm kev-iodine
Raws li cov neeg them ntau thiab ntau tus neeg ua haujlwm zoo thiab phais kev phais, qhov tseem ceeb ntawm kev phais mob kis tau ntau dua thiab muaj txiaj ntsig zoo dua. Raws li kev tiv thaiv zoo, povidone iodine muaj kev lag luam muaj zog. Nyob rau tam sim no, nws tau siv dav hauv cov tsev kho mob txhua theem, los ntawm cov tsev kho mob loj rau tsev kho mob tshwj xeeb, thiab tom qab ntawd rau cov txheej txheem kho mob. Kev Tshawb Fawb Ua Lag Luam Kev Lag Luam Kev Tshawb Fawb Txog Kev Ua Lag Luam hais tias nyob rau ob peb xyoos tom ntej no, lub ntiaj teb kev lag luam yuav loj hlob ntawm ib xyoos ib zaug ntawm 8% {%.
Nyob rau hauv cov teb kev tshawb nrhiav thiab kev txhim kho, cov neeg tshawb nrhiav paub ntau yam kev nruam thiab siv zog ua ntxiv txhim kho kev ua kom zoo thiab yooj yim ntawm kev siv ntawm kev siv lub ntsej muag iodine. Piv txwv li, tshiab kavidone iodine npaj, xws li gels thiab sprays, yog tsim kom yoog rau lwm qhov kev phais phais cov xwm txheej thiab tus neeg muaj kev xav tau. Los ntawm kev txhim kho cov qauv, txhim kho nws cov roj ntsha ua tau zoo thiab ruaj khov, nws tuaj yeem ua lub ntsej muag kev phais mob. Ib qho ntxiv, kawm cov ntawv thov sib xyaw ua ke ntawm cov tshuaj iodine nrog lwm cov tshuaj tua kab mob tshiab kuj yog ib qho ntawm kev txhim kho kev txhim kho yav tom ntej.
Hauv cov ntsiab lus xaus,Pov thawj iodineMuaj cov kev cuam tshuam loj thiab muaj txiaj ntsig zoo hauv kev tiv thaiv kev phais mob kis mob. Nws muab cov mob uas tiv thaiv kabmob thiab muaj txiaj ntsig zoo dua los ntawm kev sib txuas nrog cov tshuaj tiv thaiv kab mob. Hauv kev tshawb nrhiav kev coj ua, daim ntawv thov ntawm kev cojidone-iodine pab txo tus nqi ntawm cov kiav txhab thiab txhawb kev ua siab ntev, uas tsim nyog nce qib.